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Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

Bonn
Nordrhein-westfalen
Germany
Markus-eckstein-uniklinikum-erlangen
Uniklinikum-erlangen
Markus-eckstein
Department-of-urology
University-hospital-bonn
Institute-of-pathology
Hospital-bonn
Assistant-physician
Clinician-scientist

Oncimmune ventures into age-related disease biomarker research

Oncimmune Holdings plc, a prominent autoantibody profiling company catering to the pharmaceutical and biotechnology sectors, is expanding its horizons by delving into the realm of biomarkers for age-related diseases.

Martin-gouldstone
Pioneer-presents
Healthy-ageing
Kent-science
Clinical-development
Reclinical-research
Arkets-amp-regulations
Atient-centricity
Ata-management
Mmune-system
Ging

ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

Middlesbrough
Redcar-and-cleveland
United-kingdom
David-austin
American-college-of-cardiology
Care-research
American-college-of-cardiology-annual-scientific-session
National-institute-for-health
James-cook-university-hospital
American-college
Annual-scientific
South-tees

Heavy alcohol use linked to increased risk of Type 2 diabetes in middle-aged adults

Heavy alcohol use may increase middle-aged adults' risk of developing Type 2 diabetes, according to research to be presented this week at the American Physiology Summit in Long Beach, California.

United-states
California
Texas
American
Laura-hwang
National-institute-on-alcohol-abuse
American-physiological-society
Physiological-society
American-physiology-summit
Long-beach
National-institute
Alcohol-abuse

Focusing on oncogenic driver mutations and resistance mechanisms in the treatment of NSCLC

Lung cancer is the leading cause of cancer-related death worldwide. Improved understanding of driver mutations of non-small cell lung cancer (NSCLC) has led to more biomarker-directed treatment for patients with advanced stages.

Higher-education
Cancer
Ell
Ung-cancer
On-small-cell-lung-cancer
Mall-cell-lung-cancer
Iomarker
Rugs
Xon
Ene
Rowth-factor

Study reveals breakthrough in non-invasive detection of endometrial cancer

Study uncovers proteomic signatures in blood plasma and cervicovaginal fluid that could lead to non-invasive detection methods for endometrial cancer, demonstrating significant potential for early diagnosis and improved patient outcomes.

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Blood
Ancer
Ndometrial-cancer
Achine-learning
Roteomics
Nxiety
Iomarker
Iopsy
Leeding
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Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

Popov-shutterstock
Cancer-research
Cigarette
Na
Moking
Iomarker
Lood
Ancer
Arcinogenesis
Ell
Na-damage

Experts develop blood test that can accurately detect sleep deprivation

A blood test that can accurately detect when someone has not slept for 24 hours has been developed by experts at Monash University, in Australia, and the University of Birmingham, in the UK.

Australia
Monash
South-australia
United-kingdom
Australian
Clare-anderson
Katy-jeppe
Monash-university
Mental-health
School-of-psychological-sciences
University-of-birmingham
Monash-university-school-of-psychological-sciences

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