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Doctors home in on cause of blood clots linked with Covid-19 vaccines
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Doctors home in on cause of blood clots potentially linked with Covid-19 vaccines
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All adenoviral vector vaccine platforms are not the same, and the Johnson & Johnson COVID-19 vaccine may have different biologic characteristics and biologic effects than the AstraZeneca vaccine, researchers from Johnson & Johnson s Janssen unit argued.
In a letter to the
New England Journal of Medicine published Friday, Macaya Douoguih, MD, of Janssen Vaccines and Prevention in the Netherlands, and colleagues responded to a case report on one of the six U.S. cases of cerebral venous sinus thrombosis (CVST) with thrombocytopenia associated with the vaccine, published in
NEJM on Wednesday.
Not surprisingly, Douoguih s group asserted the cases were insufficient evidence of a causal relationship between the J&J vaccine and CVST with thrombocytopenia, claiming the rate occurs within the expected background rate for this extremely rare event. However, they went further, attempting to distance their adverse events from those associated with AstraZeneca s vacc
What we know about the super-rare blood clots linked to the J&J vaccine
Experts are figuring out how to rapidly diagnose and treat the unusual clots linked to both the Johnson & Johnson and AstraZeneca shots.
ByLinda Marsa
Email
Scientists are beginning to unravel what is sparking the rare but severe blood clotting reaction that has now been associated with both the Johnson & Johnson and the AstraZeneca coronavirus vaccines.
Called cerebral venous sinus thrombosis (CVST), this condition occurs when clots form in veins that route blood from the brain, causing strokes or other brain damage. Yesterday federal health officials recommended pausing the use of Johnson & Johnson’s single-shot vaccine after reports that six women in the United States suffered from blood clots in the brain within two weeks of vaccination. One of them died; another is hospitalized in critical condition. The pause comes on the heels of similar reports of CVST in patients in Europe who received the AstraZe
Europe lifts vaccine suspension as COVID-19 surge brings new lockdowns in France, Italy, Poland
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