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Bacterial vaginosis is the most common and recurrent gynecological condition affecting nearly 30% of women between the ages of 15 and 44, according to the U.S. Centers for Disease Control and Prevention. A University of Arizona Health Sciences-led study recently identified a specific bacteria family and uncovered how it contributes to bacterial vaginosis, paving the way for new insights into disease prevention and treatment.
Led by Melissa Herbst-Kralovetz, PhD, a member of the BIO5 Institute and associate professor of basic medical sciences at the College of Medicine - Phoenix, researchers found that members of the Veillonellaceae bacteria family contribute to an increase in inflammation and cell death, and alter the acidity of the cervical microenvironment. These changes support bacterial vaginosis and create favorable conditions for subsequent gynecological diseases, such as sexually transmitted infections and cancer.