Malaria vaccine breakthrough as promising trial rises hopes of controlling disease CNN 1 hr ago By Sharon Braithwaite, Duarte Mendonca and Tara John, CNN © Smith Collection/Gado/Getty Images Anopheles gambiae. Malaria vector, parasite. Image courtesy CDC/Jim Gathany. 1990. (Photo by Smith Collection/Gado/Getty Images).
A vaccine against malaria has shown record efficacy in a Phase II trial, a pre-print study released on Friday by Oxford University shows, raising hopes that one of the world s most deadly diseases could be brought under control.
The vaccine, developed by Oxford and known as R21, showed up to 77% efficacy in a trial of 450 children in Burkina Faso over 12 months, the university said in a statement. It said the shot was the first to meet the World Health Organization s Malaria Vaccine Technology Roadmap goal of a malaria vaccine with at least 75% efficacy.
Malaria vaccine breakthrough as promising trial rises hopes of controlling disease
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BugBitten
Multiple blood meals speed up malaria parasite development
Our findings suggest that parasites can be transmitted by younger mosquitoes, with potential consequences for increased malaria transmission and challenges to disease control strategies.
22 Jan 2021
Anopheles gambiae mosquitoes can transmit the Plasmodium parasites that cause malaria when they blood feed on people.
Photo credit: Jim Gathany, CDC
Malaria is a deadly global burden
Female
Anopheles mosquitoes transmit the
Plasmodium parasites that cause malaria. Control methods targeting mosquito populations, such as insecticide-treated bed nets, have greatly decreased the malaria burden in recent decades. Nevertheless, malaria remains a devastating cause of disease and mortality in tropical and sub-tropical regions, with over 400,000 deaths and 220 million cases in 2019. To progress further in the fight against malaria, we need a deeper understanding of the factors affecting transmission, as mosquito popul