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Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.
United States Baylor College Of Medicine Jun Li Wei Li Xing Fang Lingyong Li

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Ontology 1-Day Volume Reaches $21.98 Million (ONT)

Ontology (ONT) traded 5.6% lower against the US dollar during the one day period ending at 17:00 PM Eastern on April 9th. One Ontology coin can now be purchased for approximately $0.34 or 0.00000494 BTC on major cryptocurrency exchanges. Over the last seven days, Ontology has traded 8.4% higher against the US dollar. Ontology has […]
Jun Li Ontology Daily

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