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Wind farms to generate power and jobs for the Southern Downs Published Wednesday, 21 April, 2021 at 12:06 PM Deputy Premier and Minister for State Development, Infrastructure, Local Government and Planning The Honourable Dr Steven Miles Two windfarms and up to 400 jobs in the Southern Downs are a step closer to reality with the State Assessment and Referral Agency giving the green light. Deputy Premier and Planning Minister Steven Miles said Acciona received approval to build the $1.96 billion ...

share: This news release, issued by Johns Hopkins Medicine, describes a novel targeted immunotherapy approach. This new approach employs bispecific antibodies to treat cancer by eliciting a Tcell response against mutated p53. The researchers used the Highly Automated Macromolecular Crystallography (AMX) and Frontier Microfocusing Macromolecular Crystallography (FMX) beamlines to characterize the molecular structure of the proteins. AMX and FMX are beamlines at the National Synchrotron Li...

8th March 2021 Feature On International Women’s Day, Key.Aero explores the many women who have broken down barriers in aviation. Read on to find out which famous aviator’s couldn’t have succeeded without the help of their sister…   Beatrice ‘Tilly’ Shilling OBE (8 March 1909 – 18 November 1990)  On what would have been her birthday, there is no better place to start with our count of incredible aviation pioneers for International Women’s Day than with Beatrice S...

Novel immunotherapy approach targets cancers Appeared in BioNews 1086 Designer antibodies can alert the immune system to cancerous proteins, slowing tumour growth in mice – three independent studies demonstrate. Researchers at the John Hopkins University School of Medicine, Maryland, investigated the notorious cancer proteins, p53 and RAS. Mutations in p53 and RAS are common among cancers, however, drug therapies have been largely unsuccessful. Therefore, researchers aimed to develop specific...

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers. The researchers targeted their immunotherapy approach to alterations in the common cancer-related p53 tumor suppressor gene, th...

Two of the three research studies -- led by Jacqueline Douglass, M.D., Ph.D. candidate at the Johns Hopkins University School of Medicine and Emily Han-Chung Hsiue, M.D., Ph.D., postdoctoral fellow at Johns Hopkins--report on a precision medicine immunotherapy approach that specifically kills cancer cells by targeting mutant protein fragments presented as antigens on the cancer cell surface. Although common across cancer types, p53 mutations have not been successfully targeted with drugs. Genet...