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Junk DNA in birds may hold key to safe, effic

<p>For many genetic diseases, disabling or editing a gene using CRISPR is insufficient to overcome the effects of the underlying genetic mutation. A corrective gene needs to be added to the genome to fix the problem. UC Berkeley researchers have discovered a way to use a bird retrotransposon — a type of junk DNA — to insert whole transgenes into the human genome in a targeted way that does not risk damaging other genes.</p>

United statesVan treeckEva nogalesKathleen collinsBriana van treeckJustin shumateJeremy mcintyreXiaozhu zhangConnor hortonAkanksha thawaniHoward hughes medical instituteDepartment of molecularMethod of researchKay curci foundationUniversity of californiaNational institutes of health

Breakthrough gene therapy method utilizes bird retrotransposon for safe gene insertion

The recent approval of a CRISPR-Cas9 therapy for sickle cell disease demonstrates that gene editing tools can do a superb job knocking out genes to cure hereditary disease.

United statesBriana van treeckVan treeckJeremy mcintyreEva nogalesAkanksha thawaniJustin shumateConnor hortonKathleen collinsXiaozhu zhangUniversity of californiaDepartment of molecularKay curci foundationNational institutes of healthHoward hughes medical instituteRuth schubert family

Junk DNA in birds may hold key to safe, efficient gene therapy

Junk DNA in birds may hold key to safe, efficient gene therapy
berkeley.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from berkeley.edu Daily Mail and Mail on Sunday newspapers.

United statesXiaozhu zhangJustin shumateJeremy mcintyreAkanksha thawaniConnor hortonKathleen collinsEva nogalesVan treeckBriana van treeckUniversity of californiaNational institutes of healthDepartment of molecularHoward hughes medical instituteKay curci foundationRuth schubert family

Junk DNA in birds may hold key to safe, effic

Junk DNA in birds may hold key to safe, effic
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United statesKathleen collinsXiaozhu zhangJeremy mcintyreJustin shumateAkanksha thawaniEva nogalesVan treeckConnor hortonBriana van treeckDepartment of molecularNational institutes of healthMethod of researchUniversity of californiaHoward hughes medical instituteKay curci foundation

Researchers Develop More Sensitive At-Home Covid Test

Researchers Develop More Sensitive At-Home Covid Test
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

United statesAllen vc davisSamuel schulteNiles pierceKay curci foundationNational institutes of healthMerkin instituteJining huangTranslational researchKay curciBarbara woldLenabelle davis leadership chairBren professorChain reaction lateral flow assaysAmplified instrument free at homeNational institutes