Date Time
Scientists Identify Genetic Pathway that Suppresses Lou Gehrig’s Disease
Professor Chunghun Lim and his research team in the Department of Biological Sciences unveiled a neuroprotective pathway that suppresses Lou Gehrig’s Disease (ALS).
Nucleocytoplasmic transport (NCT) defects have been implicated in neurodegenerative diseases, such as C9ORF72-associated amyotrophic lateral sclerosis and frontotemporal dementia (C9-ALS/FTD). In this study, the research team has identified a neuroprotective pathway of like-Sm protein 12 (LSM12) and exchange protein directly activated by cyclic AMP 1 (EPAC1) that sustains the nucleocytoplasmic RAN gradient and thereby suppresses NCT dysfunction by the C9ORF72-derived poly (glycine-arginine) protein.
Network study of responses to unusualness and psychological stress during the COVID-19 outbreak in Korea
Seunghyong Ryu,
Affiliation Department of Psychiatry, Chonnam National University Medical School, Gwangju, Korea
Affiliation Gwangju Mental Health and Welfare Commission, Gwangju, Korea ⨯
Mina Kim,
Affiliation Gwangju Mental Health and Welfare Commission, Gwangju, Korea ⨯
Yu-Ri Lee, Roles Data curation, Investigation
Affiliations Gwangju Mental Health and Welfare Commission, Gwangju, Korea, Department of Social Welfare, Nambu University, Gwangju, Korea ⨯
Jonghun Lee, Roles Conceptualization, Formal analysis, Investigation
Affiliations Daegu Metropolitan Mental Health and Welfare Center, Daegu, Korea, Department of Psychiatry, Catholic University of Daegu, College of Medicine, Daegu, Korea