L Dopa News Today

Outcomes after deep brain stimulation in patients with Parkinsons disease (PD) with a mutation in the GBA gene are generally comparable to those of patients with PD not carrying this mutation.

Offering levodopa/carbidopa as a 24-hour continuous subcutaneous infusion could help to improve treatment on times and motor experiences of daily living compared with oral preparations.

A four-strain probiotic helped patients with Parkinsons disease and constipation reduce the delay in levodopa treatment effect and improve symptoms such as sleep and fatigue, in a randomized trial.

The federal Office for Human Research Protections has taken the unusual step of suspending all federally supported research at the New York State Psychiatric Institute, which is affiliated with Columbia University.

Adding singing, a pleasurable and accessible activity, to speech therapy could improve voice problems in patients with Parkinsons disease.

Called DopaFuse, the experimental device is designed to deliver the levodopa and carbidopa into the mouth through a micropump within a wearable retainer.

Continuous infusion strategies have long been sought as a method to preserve levodopa efficacy.

Patients often hide their hallucinations, which are associated with poor long-term outcomes and a reduced quality of life.

Acorda Therapeutics, Inc.

Acorda was awarded $15 million plus prejudgment interest of $1.5 million from Alkermes.