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Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that endangers almost 70 million people worldwide. The only two drugs that are currently approved for its treatment, benznidazole and nifurtimox, have controversial efficacy in adults and restricting safety issues, leaving thousands of patients without a suitable treatment. The neglect of Chagas disease is further illustrated by the lack of a robust and diverse drug discovery and development portfol...

/PRNewswire/ -- The Global Health Innovative Technology (GHIT) Fund announced today a total of approximately 750 million yen (US$6.6 million*) to invest in six...

Small Molecule Drug Discovery Market 2021: SWOT Analysis of Key Driving Factors for Growing CAGR Value | Gilead Sciences Inc.,Johnson & Johnson,AstraZeneca

Small Molecule Drug Discovery Market 2021: SWOT Analysis of Key Driving Factors for Growing CAGR Value | Gilead Sciences Inc.,Johnson & Johnson,AstraZeneca

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Abstract The K -sparing diuretic amiloride elicits anticancer activities in multiple animal models. During our recent medicinal chemistry campaign aiming to identify amiloride analogs with improved properties for potential use in cancer, we discovered novel 6-(hetero)aryl-substituted amiloride and 5-(N,N-hexamethylene)amiloride (HMA) analogs with up to 100-fold higher potencies than the parent compounds against urokinase plasminogen activator (uPA), one of amilorides putative anticancer targets...

Share this article Share this article Catheter Market has witnessed strong growth owing to the huge prevalence of cardiovascular diseases, coupled with the advancement of unique-feature enhanced cardiovascular catheters. Chronic disorders such as cardiovascular, neurology, and urology disorders have become the most imperative cause of mortality and morbidity across the globe, during the last three decades. JERSEY CITY, N.J., Feb. 8, 2021 /PRNewswire/ -- Verified Market Research recently publish...

Share this article Share this article ResearchAndMarkets.coms offering. The global metabolomics market size is projected to reach USD 4.1 billion by 2025 from USD 1.9 billion in 2020, at a CAGR of 13.4% during the forecast period. The major factors driving the growth of this market are the growing R&D expenditure in the pharmaceutical & biopharmaceutical industry, growing demand for personalized medicine, and increasing use of metabolomics in toxicology testing are driving the growth of the g...