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"Phospholipid Profiles Are Selectively Altered in the Putamen and White" by Gabrielle R. Phillips, Sarah E. Hancock et al.

Huntingtonโ€™s disease (HD) is a genetic, neurodegenerative illness that onsets in late adulthood as a series of progressive and terminal cognitive, motor, and psychiatric deficits. The disease is caused by a polyQ mutation in the Huntingtin gene (HTT), producing a polyglutamine expansion in the Huntingtin protein (HTT). HTT interacts with phospholipids in vitro; however, its interactions are changed when the protein is mutated in HD. Emerging evidence suggests that the susceptibility of brain r...
Huntingtons Disease White Matter
Source: uow.edu.au

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