Page 68 - Lipids News Today

The twincretin tirzepatide produced jaw-dropping levels of weight loss in people with obesity and no diabetes compared with placebo in the SURMOUNT-1 pivotal trial with more than 2500 participants.

Patients with diabetes should have annual screening for biomarkers of early-stage heart failure, and treatment should prioritize an SGLT2 inhibitor, said an American Diabetes Association panel.

Viruses can make animals and humans sick - or healthy: Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB have succeeded in genetically modifying the herpes simplex virus type 1, which triggers painful cold sores, in such a way that it can be used in the fight against cancer in the future.

Contrary to hints from previous research, there is no apparent venous or arterial thrombotic risk associated with higher lipoprotein(a) levels, a new study suggests.

Targeting a protein complex that inhibits lipoprotein lipase with a monoclonal antibody lowers both triglycerides and LDL cholesterol while increasing HDL cholesterol, suggests an early-stage trial.

About 3 grams daily of omega-3 fatty acids, consumed in foods or supplements, appears to be the optimal daily dose to help lower blood pressure, according to a research review published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

After many setbacks, the potential for CETP inhibition to significantly improve cholesterol levels and target attainment has been shown with obicetrapib in the ROSE trial.

Researchers have developed a novel app to show how the increased risk for coronary events due to elevated lipoprotein(a) levels can be countered by lowering LDL cholesterol levels to specific targets.

Higher scores on measures of seven cardiovascular and brain health factors are linked to lower dementia risk in middle-aged individuals at high genetic risk for the disorder, new research shows.

HDL cholesterol is classically regarded as protective against cardiovascular events, but more is not always better, as this study suggests.