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Diverse genome sequences generate a polygenic risk score to predict heart disease risk

In a large-scale study of people from diverse ancestries, researchers narrowed down the number of genomic variants that are strongly associated with blood lipid levels and generated a polygenic risk score to predict elevated low-density lipoprotein cholesterol levels, a major risk factor for heart disease.
Ann Arbor United States Cashell Jaquish Cristen Willer Charles Rotimi Emily Henderson

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Long-term risk of a major cardiovascular event by apoB, apoA-1, and the apoB/apoA-1 ratio—Experience from the Swedish AMORIS cohort: A cohort study

Göran Walldius and colleagues investigate the long-term risk of a major cardiovascular event by apoB, apoA-1 and apoB/apoA-1 ratio in the Swedish AMORIS cohort.
United States Sanjay Basu Technicon Bayer Orion Diagnostica Boehringer Mannheim Ingmar Jungner Foundation For Laboratory Medicine
Source: plos.org

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