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Ludwig Cancer Research study shows how certain macrophages dampen anti-tumor immunity

 E-Mail IMAGE: Ludwig Memorial Sloan Ketterings investigators Taha Merghoub, Jedd Wolchok and assistant attending physician Andrew Chow. view more  Credit: Ludwig Cancer Research JUNE 10, 2021, NEW YORK - A Ludwig Cancer Research study adds to growing evidence that immune cells known as macrophages inhabiting the body cavities that house our vital organs can aid tumor growth by distracting the immune systems cancer-killing CD8+ T cells. Reported in the current issue of Cancer Cell and ...
United States Charles Rudin Taha Merghoub Andrew Chow Sloan Kettering Danielk Ludwig

Suppressive immune cells' metabolic vulnerability may be targeted for cancer immunotherapy

 E-Mail IMAGE: Taha Merghoub and Jedd Wolchok of the Ludwig Center at Memorial Sloan Kettering Cancer Center (MSK) and former postdoc Roberta Zappasodi view more  Credit: Ludwig Cancer Research FEBRUARY 15, 2021, NEW YORK - A Ludwig Cancer Research study has identified a novel mechanism by which a type of cancer immunotherapy known as CTLA-4 blockade can disable suppressive immune cells to aid the destruction of certain tumors. The tumors in question are relatively less reliant on bur...
United States Taha Merghoub Roberta Zappasodi Breast Cancer Research Foundation Us National Cancer Institute Weill Cornell Medical College

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