Cureus | An Overview of Systemic Lupus Erythematosus (SLE) Pathogenesis, Classification, and Management
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with multisystem involvement. It is multifactorial and involves epigenetic, genetic, ecological, and environmental factors. Primarily it leads to activation of both innate and adaptive immunity, which consequently leads to autoreactive B cell activation by T cells and leads to immune complexes deposition in tissues leading to an autoimmune cascade that may be limited to the single organ or can cause a widespread systemic inv...
United States American College Of Rheumatology Damage Index Systemic Lupus International Collaborating Centers British Isles Lupus Assessment Group American College Of Rheumatology Systemic Lupus International Collaborating Clinics
Source: cureus.com