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Study: Common gene mutation for Parkinson's disease drives mislocalization of iron in the brain

A common gene mutation for Parkinson's disease drives mislocalization of iron in activated microglia, according to a new study publishing December 16th in the open-access journal PLOS Biology, by Mark Cookson of the National Institute on Aging and colleagues
Mark Cookson Emily Henderson National Institute On National Institute N Vivo Arkinson 39s Disease

Parkinson's Mutation Mislocalizes Iron in the Brain

The finding may help explain the accumulation of toxic iron in affected brain areas in the disease and provide a basis for the development of therapies designed to correct the iron trafficking defect. Previous data has shown that iron can be deposited in the brain, which can now be linked to a known genetic cause of Parkinson’s disease that may be relevant to novel treatments.
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