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Blood test detects childhood tumors based on their epigenetic profiles

Credit: Tatjana Hirschmugl A new study exploits the characteristic epigenetic signatures of childhood tumors to detect, classify and monitor the disease. The scientists analyzed short fragments of tumor DNA that are circulating in the blood. These "liquid biopsy" analyses exploit the unique epigenetic landscape of bone tumors and do not depend on any genetic alterations, which are rare in childhood cancers. This approach promises to improve personalized diagnostics and, possibly, future therapi...
Marie Bernkopf Sabine Taschner Mandl Perrine Marec Didier Surdez Bernadette Brennan Heidrun Boztug

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