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Oral, Daily Semaglutide Cuts Pounds in Nondiabetic Patients: OASIS 1

So far oral GLP-1 receptor analogues haven’t proved as popular as injectables in diabetes. In obesity, OASIS 1 might turn the tides.

RESPECT-EPA: Missed Primary Endpoint but Hints of Benefit With Icosapent Ethyl

Intermittent Fasting Trial Comes Out (Partly) Positive, but CV Impact Mixed

PACMAN-AMI: Positive Plaque Changes With Early Alirocumab Use in Acute MI

Statins in COVID-19: More Signs of Potential Benefit

Statins may lessen the impact COVID-19, yet another retrospective, observational study hints. Early during the pandemic in New York City, patients who were already taking statins when they were admitted for COVID-19 were less likely to die in the hospital within the first 30 days than those who were not taking the medications (14.8% vs 26.5%; OR 0.47; 95% CI 0.36-0.62), researchers report. The proportion of patients who required invasive mechanical ventilation in the first 30 days was numerically lower in the statin group, although the difference fell shy of statistical significance (18.6% vs 21.9%; OR 0.76; 95% CI 0.58-1.00), according to findings published online February 26, 2021, in Nature Communications. More of TCTMD s coverage on our COVID-19 hub.

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