Page 2 - Memory Cells News Today

>> i got breaking news for you on this today, bill. that story in the "new york times" is a big deal. it focuses on a study coming out of rockefeller university. you dont see the author in front of a microphone or taking victory lapse but in the lab throughout the pandemic studying covid and he has determined after the third booster, the third shot, the booster for the vast majority of us you get t-cells and memory cells ready to attack the virus when it comes in. who should get the fourth shot?...

With the majority of the world population being either immunized against COVID-19 or having recovered from infection, people have rightly begun to ask: How long will the immunity provide immune protection?

Longer than the first two vaccines where we knew we needed boosters five to six months later. but there are some preprint studies that show that immunity from a booster might decrease after about ten weeks, which is why youre seeing countries like israel going to a fourth shot but i will tell you, none of these studies can pick up on memory cells, which are great and have really kicked in to help protect us against infections so i think more data will come forward to show boosters last a lot lon...

You said we still need to keep the number 1 priority on getting more americans vaxed. talk to us about that. >> we havent decided if we want the vaccine. if we decide what we want from every vaccine, protection against serious illness, the kind of illness that causes you to see a doctors care or go to the icu, these vaccines do that because they create excellent memory cells. those are long-lived. so you should be protected for a while even against the omicron variant as we learned from the sout...

And so the question is, you know, whether or not, which dose is sufficient. one. but also, two, we saw with the larger dose people had adverse effects with that. the other question is how does this translate into clinical outcomes? severe disease, hospitalations, and deaths sf we dont know whether this booster has any impact yet. all we know is lab data showing increase in antibodies. we know the immune system is complicated. there are cells involved. a very sophisticated system. we know they al...

So if you are high in terms of your ability to tackle this virus antibodies you cut down lower but you still have a question. if youve vaccinate some time ago and he werent boosted and we did not test directly ourselves i think natural infections does something similar. then you may not be as well protected or maybe not protected from infection. we protected or maybe not protected from infection.— protected or maybe not protected from infection. we talk a lot on the news about — from infecti...

Shows that people who have recovered from covid have strong immunity and i mean b-cell data just this week actually and t-cell data, those are called memory cells. antibodies will actually be higher if youve had a severe infection. lower if youve had a mild infection. but they come down after vaccination anyway. its about what is cellular memory. >> isnt it, dr., gandhi, a very individualized process? in other words, millions have gotten the vaccine and theres a ton of data as to what we can exp...

Antibodies lasted longer after the pfizer booster. and it helped memory cells, immune memory cells. again, small study done by johnson & johnson. do these differences mean anything? are they significant? who knows. this has not been published in a medical journal or reviewed by anyone. people should not get fussy about what booster they get. boosters help. and it really -- it doesnt seem to matter in any significant way what booster you get. >> get boosted. elizabeth cohen, thank you very much. ...

Of people recently who are 65 years of age or others over the age of 50 with a high-risk medical condition in which case you could reasonably argue for those groups because you want to make sure you have a high level of protection against serious illness. on the other hand, and the reason thats true is because all you need for protection against serious illness is immunological memory cells, so-called memory b-cells and they are apparently induced at fairly high frequency and for years so were g...

Be harder to convince people to get because they are, by definition, one and done people? >> so the good news is that even a single dose induces immunological memory cells that are responsible for protecting against serious illness. we always talk about neutralizing antibodies. neutralizing antibodies fade over time but memory cells dont. for a long period of time -- the interesting thing about the j&j versus pfizer and moderna is really just a single dose of the j&j was able to induce excellent...