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KEYNOTE-716: Primary melanoma, not lymph nodes, should 'drive therapeutic decision-making'

CHICAGO — Adjuvant pembrolizumab showed durable benefit vs. placebo among patients with resected stage IIB or IIC melanoma, according to randomized phase 3 study results presented at ASCO Annual Meeting.After more than 3 years of follow-up, patients assigned the anti-PD-1 therapy achieved significantly longer distant metastasis-free survival (DMFS) and RFS, results of the KEYNOTE-716 trial
United States Mark Leiser Bymark Leiser Astellas Pharma Jasonj Luke Bristol Myers Squibb
Source: healio.com

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Strategy may enable some patients with HER2-positive breast cancer to avoid chemotherapy

CHICAGO — A chemotherapy de-escalation strategy involving dual HER2 blockade resulted in high rates of 3-year invasive DFS among patients with HER2-positive early breast cancer, according to study results presented at ASCO Annual Meeting.The findings appeared consistent with those of studies that explored a combination of neoadjuvant chemotherapy and dual HER2-targeted treatments, with no
United States Javier Cort Bydevin Mclaughlin Devin Mclaughlin Daiichi Sankyo Eli Lilly
Source: healio.com

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