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Pembrolizumab Plus Cisplatin/Gemcitabine Extends OS in Advanced Biliary Tract Cancer

Pembrolizumab plus cisplatin and gemcitabine produced a statistically significant and clinically meaningful improvement in overall survival vs placebo plus cisplatin and gemcitabine in previously untreated patients with advanced biliary tract cancer, according to data from the phase 3 KEYNOTE-966 trial.
United States Eli Lilly Genentech Roche Robin Kate Kelley Tyra Biosciences Department Of Medicine

'CAR T cells can eradicate solid tumors,' study in advanced neuroblastoma shows

A novel chimeric antigen receptor T-cell therapy induced clinically impactful antitumor responses in 63% of younger patients with relapsed or refractory, high-risk neuroblastoma, results of a phase 1/phase 2 trial showed.The findings, published in The New England Journal of Medicine, suggest the investigational agent also has a manageable safety profile similar to other CAR T-cell therapies,
United States Baylor College Of Medicine Oladapoo Yeku Danl Longo Ascendis Pharma Piazza Santonofrio
Source: healio.com

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Jurisdiction – Prescription drug – Warning label

Where a plaintiff claiming that he suffered injuries after prolonged ingestion of a prescription drug has filed a complaint alleging an inadequate warning label, the complaint should not be dismissed, as the defendants’ contacts with Massachusetts were sufficient to warrant the exercise of personal jurisdiction. “Richard McLaughlin (‘McLaughlin’ or ‘Plaintiff’) has brought this action against
United States Richard Mclaughlin Merck Co Inc Merck Sharp Dohme Corp Defendants Merck Co Inc Organon Co

Vaccinex Reports 2022 Financial Results and Provides Corporate Update of Continued Progress in Neurology and Oncology Clinical Programs

03.04.2023 - Expect to complete patient enrollment in the randomized Phase 1/2a SIGNAL-AD Alzheimer’s study in April 2023 with topline data anticipated mid-2024 Completed enrollment of 36 patients required for a pre-planned interim analysis of KEYNOTE B84 ...
United States United Kingdom John Mullaly Merck Kgaa Vaccinex Inc Lifesci Advisors

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