Page 2 - Methods Clinical Development News Today

Mesenchymal Stem Cells (MSCs) are emerging as a viable pathway for cancer therapy. This article discusses the challenges in utilizing MSCs for cancer therapy.

Researchers from Singapore-MIT Alliance for Research and Technology (SMART) identified a critical quality attribute that could allow the development of a rapid and sensitive process analytical technology for sterility, enabling the detection of early-stage microbial contamination in human cell therapy products (CTPs).

In this article, Sartorius demonstrates how their iQue® can be used to reliably and accurately screen for memory T cell frequency through an optimized, multiplex flow cytometry assay.

John Liddell, Chief Technologist at the Centre for Process Innovation (CPI), writes about the challenges associated with gene therapy products, which constitute a major portion of the overall cell and gene therapy market.

Researchers headed by a team at the University of California, San Diego (UCSD), School of Medicine, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD). The results of their experiments, which involved delivering a gene called SynCav1 to the mouse brain, could represent a key step toward testing the approach in humans with the neurodegenerative disorder. Reporting their results in Molecular Therapy-Methods & Clinical Development, the invest...

Researchers use gene therapy to prevent learning, memory loss in Alzheimers mouse model Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimers disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease. The findings are published online in advance of the June 11, 2021 issue of Molecular Therapy-Methods & Clinical D...

Gene Therapy in Alzheimer’s Disease Mouse Model Preserves Learning and Memory News_release Researchers at University of California San Diego School of Medicine, with colleagues elsewhere, have used gene therapy to prevent learning and memory loss in a mouse model of Alzheimer’s disease (AD), a key step toward eventually testing the approach in humans with the neurodegenerative disease. The findings are published online in advance of the June 11, 2021 issue of AD is characterized by the ...