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Evolved Proteases Selectively Cleave Target Sequences, Unlock Potential of "Proteome Editing"

Evolved Proteases Selectively Cleave Target Sequences, Unlock Potential of “Proteome Editing” February 26, 2021 Engineered botulinum toxin could lead to new treatments for a range of maladies, including nerve and brain damage, muscle injury, and rampant inflammation. [The Liu lab] Share Clostridium botulinum bacteria is responsible for producing botulinum toxin. As botox, it can remove wrinkles. It can also be the reason for a lethal human infection. Also known as the “miracle pois...
Travis Blum David Liu Thomas Dudley Cabot Michael Packer Broad Institute Harvard Medical School

'Miracle poison' for novel therapeutics

 E-Mail IMAGE: Liu and his lab engineered botulinum toxin to target new proteins, a critical advance that could lead to new treatments for a range of maladies, including nerve and brain damage,... view more  Credit: Casey Atkins Photography, courtesy of Broad Institute When people hear botulinum toxin, they often think one of two things: a cosmetic that makes frown lines disappear or a deadly poison. But the "miracle poison," as its also known, has been approved by the F.D.A. to treat...
Travis Blum David Liu Michael Packer Broad Institute Department Of Chemistry Harvard University

CNBC Closing Bell August 27, 2012

we had a comeback around noontime today. down five points. right now on the dow, 13, 1, 52. nasdaq today is positive. you can guess apple is among the gainers there. after winning that patent suit late friday night against samsung. and apple has been up about 2% today. nasdaq is up eight points now at 3,077. s&p 500 index is up two points at 1413. >> so bill hinted why 7500 and -- the nasdaq are higher. there it is. apple, new all-time high today after winning the sweeping victory in t...
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CNBC Squawk On The Street August 16, 2012

lukewarm guidance. are the best days over after a steep climb this year? >> a massive dividend hike, sending cisco shares higher, the company sounding more optimistic, but does it focus on capital returns signal slowing growth? >> today is the day facebooks first lockup expiration is here, potentially sending 10% of its hope to the market. we are tracking the fb trade. >> and a microphone always helps me. appletv, more than a settop box? well have the latest. lets start off with walm...
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CNBC Squawk On The Street August 2, 2012

markets this morning. the german diamondbacks doax do percentage points. we are half an hour into the press conference. mario draghi says the euro irreversible and that government should be ready to activate the esff. well have the latest. knight capital shares continue their free-fall this morning, the company saying the erroneous trade positions resulted in a loss and that its capital base has been severely impacted. retailers on the move this morning, costco beating estimates. steve...
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CNBC Closing Bell With Maria Bartiromo July 5, 2012

is housing, mortgage rates at record lows, havacancies are at decade low. >> in the meantime, this is how we are settling out. the down was down 91, the lows at the open this morning, the s&p down six points and the nasdaq holding on to a gain, and technology was relatively strong, but all of that changing tomorrow because now that the markets are closed for today, the countdown is on for the all important jobs number for june. while no one knows what number will be, someone here says ...
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