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How "paralyzed" immune cells can be reactivated against brain tumors

Brain tumor cells with a certain common mutation reprogram invading immune cells. This leads to the paralysis of the bodys immune defense against the tumor in the brain. Researchers from Heidelberg, Mannheim, and Freiburg discovered this mechanism and at the same time identified a way of reactivating the paralyzed immune system to fight the tumor. These results confirm that therapeutic vaccines or immunotherapies are more effective against brain tumors if active substances are simultaneously use...
Baden Wüberg Michael Platten Ilona Gutcher Stefan Pusch Oliver Schnell Felix Sahm

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