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PHILADELPHIA — Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA

PHILADELPHIA — Messenger RNA became a household term when it was used as the backbone of the first COVID-19 vaccines, especially after the Nobel Prize was awarded to two mRNA

Recent research reveals a breakthrough in lung repair, showing how delivering VEGFA via lipid nanoparticles can significantly repair damaged blood vessels, akin to plumbing repairs. This method, validated in animal models, offers promising insights into treating respiratory virus damages, enhancing

Feng Zhang’s lab has unveiled a new tool that could be a game changer for the therapeutic delivery of biomolecules: a bacterial "syringe."

Breakthrough medical technology like mRNA vaccines rely on tiny nanoparticles to deliver medicine to cells. A new device will help drug manufacturers and evaluators like the FDA more precisely measure genetic payloads to evaluate drug effectiveness.

Wednesday, March 2 at 10am ET / 3pm GMT / 4pm CET...

Pioneering COVID-19 vaccines could lead to cures The RNA jabs developed to fight coronavirus also have potential to treat other maladies including cancer and rare genetic diseases diagnosed in the womb. Long before the coronavirus, scientists envisioned using RNA to treat a variety of human diseases, including cystic fibrosis and sickle-cell anaemia.  Getty Share A few weeks ago, a group of scientists reported that they had injected mice with genetic instructions in the form of RNA, prompting ...

RNA worked for COVID-19 vaccines. Could it be used to treat cancer and rare childhood diseases? Tom Avril, The Philadelphia Inquirer A few weeks ago, a group of Philadelphia scientists reported that they had injected mice with genetic instructions in the form of RNA, prompting the animals’ cells to produce customized proteins. If that seems like no big deal at this point, now that millions have undergone a similar process in being vaccinated against COVID-19, guess again. Thes...

/PRNewswire/ -- Researchers at Childrens Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have...

Credit: Childrens Hospital of Philadelphia Philadelphia, January 13, 2021--Researchers at Childrens Hospital of Philadelphia and the School of Engineering and Applied Science at the University of Pennsylvania have identified ionizable lipid nanoparticles that could be used to deliver mRNA as part of fetal therapy. The proof-of-concept study, published today in Science Advances, engineered and screened a number of lipid nanoparticle formulations for targeting mouse fetal organs and has laid the...