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Sequencing key in 'race' against variants, experts say

The many COVID-19 variants that have been spreading around the globe and here in Massachusetts could have ramifications for the states economic reopening and vaccination efforts, but first the Bay State needs to get a better snapshot of how prevalent these mutants are, experts told lawmakers Tuesday. The U.S. Centers for Disease Control and Prevention has identified five unique mutations of the COVID-19 virus as "variants of concern," meaning theres evidence that these circulating strains could...
Bay State United States Boston University United Kingdom South Africa Nahid Bhadelia

Connecting enhancer variants, genes, and disease; synthetic spike binders; measuring tumors' cellular mix; and more

Posted April 9th, 2021 for Broad Institute Welcome to the April 9, 2021 installment of Research Roundup , a recurring snapshot of recent studies published by scientists at the Broad Institute and their collaborators. Enhancing V2F maps GWASs have yielded thousands of genetic variants linked to disease. To help figure out the function of many of these variants, Joseph Nasser (now at Caltech), Drew Bergman, Charles Fulco (now at Bristol Myers Squibb), Philine Guckelberger (now at...
Joseph Nasser Wendy Garrett Harvard Chan Microbiome Curtis Huttenhower Stefan Dentro Guoping Feng

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