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G-CON Welcomes James Schmidt as Chief Commercial Officer

College Station, TX (PRWEB) June 06, 2023 G-CON, the global leader in off-site prefabricated cleanroom systems, today announced that it is expanding its

IJMS | Free Full-Text | Understanding of Ovarian Cancer Cell-Derived Exosome Tropism for Future Therapeutic Applications

Exosomes, a subtype of extracellular vesicles, ranging from 50 to 200 nm in diameter, and mediate cell-to-cell communication in normal biological and pathological processes. Exosomes derived from tumors have multiple functions in cancer progression, resistance, and metastasis through cancer exosome-derived tropism. However, there is no quantitative information on cancer exosome-derived tropism. Such data would be highly beneficial to guide cancer therapy by inhibiting exosome release and/or uptake. Using two fluorescent protein (mKate2) transfected ovarian cancer cell lines (OVCA4 and OVCA8), cancer exosome tropism was quantified by measuring the released exosome from ovarian cancer cells and determining the uptake of exosomes into parental ovarian cancer cells, 3D spheroids, and tumors in tumor-bearing mice. The OVCA4 cells release 50 to 200 exosomes per cell, and the OVCA8 cells do 300 to 560 per cell. The uptake of exosomes by parental ovarian cancer cells is many-fold higher than b

Monadnock Ledger-Transcript - BUSINESS QUARTERLY: Lack of housing in the state leaving people with few options

In Peterborough, the vacancy rate is 0.0 percent. Town Planner Danica Melone said in a healthy market, that number should be closer to 5 or 6 percent. When Melone occasionally sees rentals pop up, they’re usually rented within a day. She said she has.

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