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Despite higher pain scores at 8 hours postoperatively and increased opioid use, local infiltration analgesia was less costly and yielded similar pain scores at 24 hours after shoulder arthroplasty compared with an interscalene block.In a level-1, prospective randomized trial, Michael Ewing, MD, and colleagues from the University of Missouri compared outcomes between 37 patients who underwent

The FDA granted priority review to mosunetuzumab for treatment of certain patients with relapsed or refractory follicular lymphoma.The designation applies to use of the agent by adults who received at least two prior systemic therapies.

Individuals aged 65 years and older with a history of hypothyroidism were associated with an 81% increased risk for dementia, researchers reported in Neurology. “In some cases, thyroid disorders have been associated with dementia symptoms that can be reversible with treatment,” Chien-Hsiang Weng, MD, MPH, clinical assistant professor at Brown University Warren Alpert Medical School

Drugs that target the noradrenergic system may improve cognition and apathy in patients with dementia or mild cognitive impairment caused by Alzheimer’s disease but have little effect on attention or episodic memory, researchers reported. Michael C. B. David, MBBS, a research fellow and PhD candidate at Imperial College London, and colleagues aimed to assess the efficacy of drugs with

Researchers identified five common themes among Indigenous patients with chronic kidney disease when exploring their relationship with health care, according to data published in Kidney International.“Indigenous peoples are defined as those who first lived in a region and have distinct cultural traditions, knowledge and language which provides a basis for positive self-image and healthy

Results showed the addition of a single-injection proximal sciatic nerve block to an adductor canal block significantly reduced pain and opioid requirements in pediatric patients undergoing medial patellofemoral ligament reconstruction.Researchers performed a retrospective cohort study on 144 pediatric patients who underwent (MPFL reconstruction with peripheral nerve blockade for postoperative

More than one-third of patients treated for differentiated thyroid cancer reported elevated anxiety and more than 15% reported a high level of depression at an annual follow-up, according to study findings published in Thyroid.In an analysis of data from more than 600 survivors of differentiated thyroid cancer at a clinic in Germany, permanent hypoparathyroidism was a predictor for high anxiety

Once-daily fixed combination bimatoprost, timolol and brimonidine more effectively reduced peak IOP compared with a twice-daily regimen in patients with primary open-angle glaucoma, according to a study in the Journal of Glaucoma.

Electroconvulsive therapy was associated with improvement of symptoms in those with mania, with higher response rates in those more seriously ill and without comorbid anxiety or obsessive-compulsive disorder, per a recently published study.“Most guidelines recommend electroconvulsive therapy (ECT) as a second-line treatment for mania,” Katarzyna Popiolek, MD, of the University Health

Induction chemotherapy with paclitaxel, cisplatin and capecitabine vs. cisplatin and fluorouracil improved failure-free survival among patients with advanced nasopharyngeal carcinoma, according to a study published in JAMA Oncology.Results of the randomized, open-label, phase 3 trial also showed the paclitaxel combination did not result in a higher rate of serious adverse events, researchers