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Bortezomib extends survival of children with newly diagnosed T-cell lymphoblastic lymphoma

The addition of bortezomib to chemotherapy significantly improved survival outcomes among children and young adults with T-cell lymphoblastic lymphoma, according to phase 3 study results published in Journal of Clinical Oncology. Additionally, radiation can be eliminated in 90% of children with T-cell acute lymphoblastic leukemia with the intensified chemotherapy regimen, researchers noted.
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Source: healio.com

More pain, medication use seen with spinal vs. general anesthesia for hip fracture surgery

Published results showed use of spinal anesthesia during hip fracture surgery led to more pain in the first 24 hours and use of more prescription analgesia at 60 days compared with general anesthesia.“In our study, patients who got spinal anesthesia did get fewer opioids in the operating room, but they ended up having more pain and more prescription pain medication use after surgery,”
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Source: healio.com

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Common endocrine-disrupting chemicals may drive incident hypertension in midlife women

Women exposed to higher concentrations of a class of endocrine-disrupting chemicals known as perfluoroalkyl and polyfluoroalkyl substances are at increased risk for incident hypertension, researchers reported.Data show human exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS) may be associated with higher risk for CVD and peripheral artery disease, as well as several CVD risk factors
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Source: healio.com

Diabetes may worsen longer-term survival for adults with breast cancer

ATLANTA — Presence of diabetes and worse glycemic control were not associated with breast cancer outcomes until 8 years of follow-up, when survival rates worsened for patients with diabetes, according to study data.“In the first 5 years, glycemic control may not be a major contributor to mortality or cancer progression in most individuals with metastatic breast cancer,” Y.M.
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Source: healio.com

Greater fracture risk seen with insulin vs. metformin use for adults with type 2 diabetes

ATLANTA — Adults with type 2 diabetes who were prescribed insulin had greater risks for major osteoporotic and hip fractures than those prescribed metformin, according to study data.“Patients using insulin or sulfonylurea are at a high risk of fractures compared to metformin-only users, and the risk could be higher in nonobese and well-controlled diabetic patients,” Sung Hye
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Source: healio.com

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