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Q&A: Identifying, treating rare mucosal melanoma

Mucosal melanoma — or melanoma in the mucous membranes — differs from cutaneous melanoma in its genesis, its treatment and its severity. Sometimes called a “hidden cancer,” mucosal melanoma is often more deadly than cutaneous melanoma. It is difficult to diagnose and often not found until the later stages, making treatment and survival more difficult.
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Source: healio.com

Chalazion rate highest among Hispanic/Latino, American Indian, Asian children

Among children of all racial and ethnic groups, Hispanic/Latino, American Indian and Asian children developed chalazion at a higher rate, and those with meibomian gland disease or blepharitis were more likely to develop chalazia on multiple occasions.“Identifying those at higher risk of chalazion formation, recurrent chalazion and chalazion requiring surgery (often including general
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Source: healio.com

FDA approves inhaled treprostinil for treatment of PAH, pulmonary hypertension-ILD

United Therapeutics Corp. announced that the FDA has approved the Tyvaso dry powder inhaler for the treatment of pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease to improve exercise ability.Tyvaso DPI represents a new formulation and inhalation device for inhaled treprostinil and is the only dry powder inhaler approved by the FDA for use in PAH
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Source: healio.com

CAR-T shows 'remarkable' efficacy as first-line therapy for large B-cell lymphoma

First-line therapy with axicabtagene ciloleucel induced objective responses in 89% of patients with high-risk large B-cell lymphoma, according to phase 2 study results.An estimated 91% of patients treated with a single infusion of the chimeric antigen receptor T-cell therapy remained alive at 12 months, a primary analysis of the ZUMA-12 trial showed.
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Source: healio.com

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Symptom onset, mortality linked for those with Down syndrome, autosomal dominant AD

Age variability in symptom onset of Alzheimer’s disease in those with Down syndrome was comparable to those who experienced autosomal dominant AD, while mortality was also similar, according to a study published in JAMA Network Open. “Down syndrome is a complex condition with multiple associated comorbidities that vary throughout the lifespan. Improvements in health care ... have
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Source: healio.com

'Clinically meaningful' results seen with tralokinumab

For some atopic dermatitis patients treated with tralokinumab who do not reach clear or almost clear skin, clinically meaningful results can still occur. “The FDA approves drugs in atopic dermatitis based solely on the proportion of patients or percentage of patients who get clear or almost clear after 16 weeks of treatment,” Eric Simpson, MD, director of the clinical studies unit at
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Source: healio.com

Interdisciplinary care led to transplant listings for underrepresented groups with ESKD

Interdisciplinary care was associated with higher odds of being listed for kidney transplant among patients with incident end-stage kidney disease in underrepresented groups, according to this study.Further, researchers found interdisciplinary care provides better ESKD preparedness than the usual nephrology care in this population.
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Source: healio.com

Study characterizes food protein-induced enterocolitis syndrome in adults

Adults and children have different experiences with food protein-induced enterocolitis syndrome, although more research is necessary, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice. Specifically, unlike what has been document in the pediatric population, the adult cohort less frequently experienced vomiting, severe acute episodes and development of
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Source: healio.com

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