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No increased CV, death risk with ticagrelor plus proton pump inhibitor therapy after PCI

Concomitant proton pump inhibitor plus ticagrelor monotherapy after PCI does not increase risk for all-cause death or an adverse CV event, in contrast with conventional post-PCI antiplatelet therapy, researchers reported.In a post hoc analysis of the GLOBAL LEADERS trial, researchers found that patients taking a proton pump inhibitor (PPI) treated with the conventional post-PCI treatment strategy
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Source: healio.com

'Communication is key' to reduce suicide risk after cancer diagnosis

Hemonc Today | Studies consistently have shown patients with cancer have a higher risk for suicide than the general public.A population-based study of more than 4.6 million patients with cancer showed an excess risk for suicide within 1 year after diagnosis of 2.51 per 10,000 person-years. In that study, published in 2019 in Cancer, Saad and colleagues observed the highest increases in suicide rates following
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Source: healio.com

LOGICS: Levoketoconazole improves cortisol control in endogenous Cushing's syndrome

SAN DIEGO — Compared with placebo, levoketoconazole improved cortisol control and serum cholesterol levels for adults with endogenous Cushing’s syndrome, according to results from the LOGICS study presented here. Safety and efficacy of levoketoconazole (Recorlev, Xeris Biopharma) for treatment of Cushing’s syndrome were established in the pivotal phase 3, open-label SONICS
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Source: healio.com

Quality-of-care program improved clinician adherence to acute ischemic stroke guidelines

Implementation of an interactive training program increased clinician adherence to stroke guidelines and reduced the proportion of disabled or deceased patients with acute ischemic stroke, researchers reported in JAMA Network Open. “Although evidence-based clinical stroke guidelines provide recommendations for stroke treatments, gaps exist between the guideline recommendations and clinical
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Source: healio.com

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Immunosuppressive drugs in atopic dermatitis do not reduce COVID-19 vaccine efficacy

Immunosuppressive drugs for the treatment of atopic dermatitis did not reduce protection conferred by messenger RNA COVID-19 vaccination, according to a study. “The effectiveness of messenger RNA coronavirus disease 2019 (COVID-19) vaccines in patients with atopic dermatitis (AD) is yet to be delineated,” Khalaf Kridin, MD, of the unit of dermatology and skin research laboratory at
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Source: healio.com

Chronic respiratory symptoms in young adulthood increase risk for later-life CVD, mortality

Chronic respiratory symptoms in young adulthood were associated with increased risk for cardiovascular disease and all-cause mortality in midlife, independent of CV risk factors, smoking and lung function, researchers reported in Chest.“Little evidence currently exists regarding the association between chronic respiratory symptoms in young adulthood and cardiovascular outcomes in
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Source: healio.com

Individuals with long COVID-19 may be at greater risk for abnormal blood clotting

Individuals with long COVID may have a higher risk for abnormal blood clotting, especially those who have difficulties with basic exercise for more than 12 weeks after infection, according to a study published in Blood Advances. The findings highlight a potential role for antithrombotic therapy in the management of these patients, researchers noted.
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Source: healio.com

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