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Same-day discharge for AF ablation increases, improving efficiency over time

An analysis of single-center data showed same-day discharge after atrial fibrillation ablation increased from 2020 to 2021, with reduction in total time spent in-hospital and no change in readmission rates for adverse events. Same-day discharge after AF ablation may be associated with improved patient satisfaction and reduced hospital resource utilization, Bruce A. Koplan, MD, MPH, FHRS, a
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Source: healio.com

Fast-track rehabilitation after THR yielded shorter stays, better functional outcomes

Patients who received fast-track rehabilitation after total hip replacement experienced shorter hospital stays and better functional outcomes compared with patients who had conventional rehabilitation, according to results.Researchers randomly assigned 60 patients undergoing THR for hip arthritis to participate in conventional rehabilitation after a normal hospital stay or a fast-track
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Those with psychiatric illness less likely to be tested, vaccinated than general population

Those hospitalized for psychiatric illness were less likely to be tested for COVID-19 and had lower confirmed infection rates but higher risk for COVID-19-related mortality than the general population, per a study from Molecular Psychiatry. “Many authors have recommended prioritization of COVID-19 vaccination for people with severe mental illness, and some but not all studies reported lower
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Ibrutinib shows promise for children with chronic graft-versus-host disease

SALT LAKE CITY — Ibrutinib appeared safe and effective for children with previously untreated or relapsed/refractory chronic graft-versus-host disease, according to study results. Paul A. Carpenter, MD, professor at Fred Hutchinson Cancer Research Center, presented the results at Tandem Meetings | Transplantation & Cellular Therapy Meetings of ASTCT and CIBMTR.
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Source: healio.com

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FDA approves mavacamten, first treatment for obstructive hypertrophic cardiomyopathy

The FDA approved mavacamten for the treatment of symptomatic, obstructive hypertrophic cardiomyopathy, the first cardiac myosin inhibitor to be permitted for use in the United States, Bristol Myers Squibb announced.Mavacamten (Camzyos, Bristol Myers Squibb) is the first and only FDA-approved allosteric and reversible inhibitor selective for cardiac myosin that targets the underlying
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Source: healio.com

Erythematotelangiectatic, papulopustular rosacea most common of four major subtypes

Erythematotelangiectatic and papulopustular rosacea were found to be the chronic skin condition’s most common subtypes, according to a systematic review and meta-analysis. “Four distinct rosacea subtypes have traditionally been recognized, but the frequency of these subtypes among patients with rosacea remains unknown,” Yousef A. Barakji, MS, of the department of dermatology at
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Unique food allergy conference aims to connect clinicians, families with experts

Families and clinicians alike often have questions about care when it comes to food allergies, from understanding cutting-edge treatments such as oral immunotherapy to addressing psychosocial burdens such as phobias and bullying. Answers and more can be found at the Food Allergy Conference for Education & Science (FACES) from June 10 to 11 in Chicago, according to its host, the Center for
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Source: healio.com

FDA grants orphan drug designation to off-the-shelf CAR-T for advanced multiple myeloma

The FDA granted orphan drug designation to ALLO-605, a chimeric antigen receptor T-cell therapy for adults with relapsed or refractory multiple myeloma.ALLO-605 (Allogene Therapeutics) is an allogeneic, gene-edited CAR T-cell therapy that targets the B-cell maturation antigen (BCMA) on the surface of cancer cells. The investigational agent was previously given fast track designation by the FDA.
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Factors predict survival after immunotherapy combination for HNSCC

DALLAS — Multiple factors predicted improved survival among patients with head and neck or salivary gland cancers treated with pembrolizumab plus vorinostat, according to prospective study results.Patients with lower pretreatment neutrophils and neutrophil-to-lymphocyte ratios — as well as those with more pretreatment lymphocytes and T helper cells — achieved longer OS and PFS,
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