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Molecular signature response classifier-assisted rheumatoid arthritis treatment selection may improve real-world results in patients with rheumatoid arthritis, according to data published in Expert Opinion on Biological Therapy. “This study reports the second interim analysis of the [Accelerate Information of Molecular Signatures (AIMS)] real-world study evaluating the clinical utility of

The FDA granted fast track designation to PDS0101 for treatment of certain patients with head and neck cancer.The designation applies to use of the agent in combination with pembrolizumab (Keytruda, Merck) by patients with recurrent or metastatic HPV16-positive disease.

LONDON — Patients with nonalcoholic fatty liver disease had worse health-related quality of life, regardless of fibrosis stage, compared with the general population, according to research presented at the International Liver Congress. “Health-related quality of life has been shown to be impaired in NAFLD patients and potentially associated with fibrosis severity, obesity or other

LONDON — The Gender-Equity Model for Liver Allocation and its sodium-corrected variant were better predictors of mortality or delisting in patients awaiting liver transplantation and may correct gender disparities, according to research. “The odds of delisting for sickness in women are 30% higher than in men, and this may have something to do with serum creatinine,” Manuel

A high degree of social anxiety was reported among Lebanese adolescents and was attributed to factors such as parental separation, neglect and child abuse, according to a study published in the Journal of Clinical Psychiatry. “Social anxiety disorder is a growing problem among adolescents in different communities, with a high prevalence in Lebanon, an early age at onset, and some

Erik Knudsen, PhD, has been appointed associate director of basic science research at Roswell Park Comprehensive Cancer Center.Knudsen — a faculty leader at Roswell Park since 2018 — will continue to serve as chair of molecular and cellular biology.

Infants aged younger than 6 months were better protected from serious COVID-19 outcomes if their mothers received two doses of the vaccine while pregnant, according to researchers. Maternal vaccination during pregnancy reduced the infant’s risk for COVID-19-related hospitalization by more than 50%, Natasha B. Halasa, MD, MPH, a professor of pediatrics at Vanderbilt University, and

Lower BMI at the time of surgery was associated with increased functional improvements for patients undergoing total joint arthroplasty, thus patients should focus on optimizing preoperative BMI, according to published results.To determine the effect of postoperative weight change on outcomes after TJA, Laura A. Stock, MS, and colleagues retrospectively analyzed data on 988 patients who underwent

LONDON — Although the annual incidence of acute hepatitis C virus has decreased over the past 10 years in Frankfurt, Germany, the prevalence of HCV genotype 4 increased in men who have sex with men, according to research.

High levels of exposure to fine particulate matter during specific prenatal and postnatal developmental windows may increase the risk for childhood asthma and wheezing, according to a study published in Pediatric Allergy and Immunology. Targeted measures to reduce exposure to these pollutants are needed to lower these risks, Guimin Chen, of the School of Public Health at Southern Medical