Page 2 - Mortality Longevity News Today

The five-year survival rate for people on dialysis is under 50 percent. University of California researchers are hoping to improve that prognosis.

 E-Mail A new analysis of adults aged 80 years and older shows that a healthier lifestyle is associated with a lower risk of cognitive impairment, and that this link does not depend on whether a person carries a particular form of the gene APOE. Xurui Jin of Duke Kunshan University in Jiangsu, China, and colleagues present these findings in the open-access journal PLOS Medicine. The APOE gene comes in several different forms, and people with a form known as APOE ε4 have an increased risk of ...

Transgenic mice express high levels of the SIRT6 gene and show that their life expectancy can be increased by an average of 30% in both males and females. The mice exhibited significant improvement in overcoming a variety of age-related diseases and conducted the same level of vigorous activity as young mice, without becoming frail. Through a variety of methods and analyses, the mechanism through which SIRT6 facilitates healthy aging was deciphered.

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through th...

 E-Mail While some studies suggest female patients treated by female physicians have better outcomes, there does not appear to be a relationship between operator and patient gender and outcome in patients undergoing coronary angioplasty or stenting. These are the results of a first-of-its-kind study by the Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2) and published in Catheterizations and Cardiovascular Interventions. The study looked at procedures performed by 385 male ...

(doi:10.1001/jamainternmed.2021.2209) Editors Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support. ### Media advisory: The full study is linked to this news release. Embed this link to provide your readers free access to the full-text article This link will be live at the embargo t...

For many diseases, overweight and obesity are risk factors. But now a study shows that a higher BMI may be linked to higher survival rates in patients hospitalized for severe bacterial infections.

 E-Mail COLUMBUS, Ohio - Though obesity in midlife is linked to an increased risk for Alzheimers disease, new research suggests that a high body mass index later in life doesnt necessarily translate to greater chances of developing the brain disease. In the study, researchers compared data from two groups of people who had been diagnosed with mild cognitive impairment - half whose disease progressed to Alzheimers in 24 months and half whose condition did not worsen. The researchers zeroed in o...

(doi:10.1001/jamacardio.2021.0487) Editors Note: The article includes conflict of interest disclosures. Please see the articles for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support. #  #  # Media advisory: The full study and commentary are linked to this news release. ### Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by ...

Credit: Newcastle University, UK New research has shown that people with type 1 diabetes may have features of premature heart disease induced by the condition often before they even get their diagnosis. Early markers for this heart disease could be used to ensure patients get targeted therapies as soon as they are diagnosed with type 1 diabetes to slow down or even halt cardiovascular problems. The findings, published in Stem Cell Research and Therapy, show that tiny pieces of genetic material...