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Where Big Pharmas Faltered, Stemline Succeeds and Lands FDA Nod in Breast Cancer

Orserdu, a drug from Menarini Group subsidiary Stemline Therapeutics, is now approved for treating breast cancers that carry the ESR1 mutation. The drug is the first approved oral therapy from a class of therapies called selective estrogen receptor degraders (SERDS).
United States Michael Wang Aditya Bardia Eli Lilly Guardant Health University Of Texas Md Anderson Cancer Center

Healthcare Consumers and Leaders Are Disserved by Subjective and Perception-based Rankings

Instead of leaning on the arbitrary and subjective nature of prominent, perceived prestige-focused industry rankings, health systems must shift to a data-driven and mathematically sound approach to determining and benchmarking quality.
Karen Joynt Maddox Centers For Medicare Medicaid Service Lown Institute Washington University In St World Report

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Paradigm Launches with $203M to Transform Clinical Trial Recruitment

Paradigm, a new startup co-incubated by ARCH Venture Partners and General Catalyst, recently launched with $203 million in Series A funding. The company is focused on improving equitable access to trials by creating a less fragmented and more efficient clinical research ecosystem.
United States Kent Thoelke American Cancer Society Brightedge Clara Health Monogram Health General Catalyst

FDA Asks Gene Therapy Biotech to Run Clinical Trial That Might Be Impossible

Taysha Gene Therapies has encouraging data from an open-label, Phase 1/2 study in the rare disease giant axonal neuropathy. It might not be enough. The FDA recommended the biotech conduct a randomized and placebo-controlled studyโ€”a challenge in any ultra-rare disease.
Sami Corwin Raju Prasad William Blair Rd Sukumar Nagendran Sean Nolan National Institutes Of Health

Russian Hackers Take Down At Least 17 U.S. Health System Websites

Russian hacker group Killnet has claimed responsibility for a string of recent cyberattacks that took more than a dozen hospital websites offline across the U.S. โ€” including the websites for Cedars-Sinai, Michigan Medicine, and UPMC. The group has been active for at least a year and is known to target countries that support and/or send resources to Ukraine.
North Carolina United States New Hampshire New Jersey South Carolina Anmed Anderson

Ciox, Sentara Healthcare Pilot Data Access Tool to Improve Maternal Health

Ciox recently partnered with Virginia-based non-profit health system Sentara Healthcare to pilot a tool that makes it easier for expectant mothers to access their health records. The fact that patientsโ€™ pregnancy data get trapped in silos is problematic because providers can use that information to predict complications and intervene sooner.
United States White House District Of Columbia Department Of Health Human Services Sentara Healthcare

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