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Ionis Posts Trial Data in Rare Disease That Position It to Finally Set Out on Its Own

Ionis Pharmaceuticals’ olezarsen has Phase 3 results showing the therapy handily beat a placebo at reducing fat levels in the blood due to a rare, inherited metabolic disorder with no FDA-approved drugs. Ionis plans early 2024 submissions for what could become the first medicine it commercializes without a partner.
Sam Tsimikas Ionis Pharmaceuticals California Based Ionis Akcea Therapeutics Weight Loss Medical Devices

Nursing Homes, Beware! Supreme Court Greenlights Civil Lawsuits to Enforce FNHRA

The Supreme Court’s recent summer decision in Health and Hospital Corporation of Marion County, Indiana, et al. v. Talevski has raised the stakes for nursing homes by ruling that private litigants may bring civil claims against facilities to recover damages for violations of certain provisions of the Federal Nursing Home Reform Act (FNHRA). This decision provides powerful incentives for nursing homes and other facilities subject to the FNHRA to enhance their monitoring and compliance processes...
Marion County United States Circuit Court Hospital Corporation Of Marion Supreme Court Hospital Corporation

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Intermountain CEO: You Don't Have To Be a Payvider to Reach Scale in VBC

The advancement of value-based care cannot and should not exist solely in a payvider model, Intermountain Health CEO Rob Allen argued in an interview last week. Having its own health plan made things “a little easier” when Intermountain began getting serious about at-risk contracts, but achieving success in value-based care “is more about your commitment to the approach" and forging strong relationships with payers of all types.
United States Rob Allen Samera Health Intermountain Health Select Health Tellica Imaging

After NASH Hopes Are Dashed, Intercept Pharma Agrees to $794M Buyout

Intercept Pharmaceuticals’ acquisition by Alfasigma comes three months after the FDA again rejected the biotech’s drug as a treatment for the fatty liver disease NASH. But Intercept still has rare liver disease assets, and Italy-based Alfasigma says acquiring the company will help it expand in gastroenterology and hepatology.
New Jersey United States New York Francesco Balestrieri Roberto Pellicciari University Of Perugia

Contamination Risk Sparks a Recall of GSK, Scynexis Antifungal Drug

Scynexis said no adverse events or contamination problems have been reported for Brexafemme, an antifungal approved for treating vaginal yeast infections. The biotech said the risk of cross-contamination stems from the processes of the small molecule’s third-party manufacturer.
Jersey City New Jersey Based Scynexis Weight Loss Medical Devices Healthcare Innovation Medcity News

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