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Familial Hypercholesterolemia May Double Coronary Heart Disease Risk in Moderately Elevated LDL-C

However, the association between familial hypercholesterolemia variants and coronary heart disease slightly weakened after adjusting for baseline low-density lipoprotein cholesterol (LDL-C) level and became statistically insignificant after adjusting for cumulative past LDL-C exposure.
Artery Risk Development In Young Adults Cardiovascular Health Study Atherosclerosis Risk Coronary Artery Risk Development Young Adults Framingham Heart Study Offspring
Source: ajmc.com

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