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FDA alerts health care providers and clinical laboratory staff about SARS-CoV-2 viral mutation

The U.S. Food and Drug Administration is alerting clinical laboratory staff and health care providers that the FDA is monitoring the potential impact of viral mutations, including an emerging variant from the United Kingdom known as the B.1.1.7 variant, on authorized SARS-CoV-2 molecular tests, and that false negative results can occur with any molecular test for the detection of SARS-CoV-2 if a mutation occurs in the part of the virus's genome assessed by that test.
United Kingdom Emily Henderson Drug Administration Health Care Sars Cov 2 ஒன்றுபட்டது கிஂக்டம்

Genome sequencing helps nail virus spread, mutation | India News

NEW DELHI: As the new UK variant of coronavirus worries governments, India is keenly looking at the mutation in order to find out to what extent the altered virus can influence transmission, clinical outcomes, severity and the need for specific public health intervention measures. TOIspoke to experts to understand what genome surveillance is and how it assesses impact of virus mutations. For genome sequencing, a swab sample collected through RT-PCR is used to amplify the virus to identify whe...
United Kingdom Raman Gangakhedkar Varsha Potdar National Institute Of Virology Indian Council Of Medical Research National Influenza Centre

Potential treatment approach to new COVID-19 variant

Potential treatment approach to new COVID-19 variant Researchers in the United States have demonstrated a potential new approach to treating infection with the new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19). The team used all-atom molecular dynamics to explore the mechanisms underlying the increased infectivity and spread of the recently emerged B.1.1.7 lineage that has been designated a variant of concer...
United States New York Neoland Biosciences Binquan Luan Sally Robertson Thomasj Watson Research Center

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High-affinity SARS-CoV-2 RBD drives mutation spread, forms basis of new COVID-19 inhibitor

Now, an intriguing recent study appeared on the bioRxiv * preprint server describes the use of in vitro evolution to elicit affinity maturation of the viral receptor-binding domain (RBD) of the spike protein to bind the host cell angiotensin-converting enzyme 2 (ACE2) with greater affinity.
South Africa United Kingdom South African Liji Thomas Global Initiative For Sharing All Influenza Data Global Initiative

New COVID 'Super Strains' Could Disrupt Life Again

New COVID ‘Super Strains’ Could Disrupt Life Again Jan. 6, 2021 -- After 10 months of masks, social distancing, virtual school, fear for vulnerable loved ones, and loneliness, this is the news no one wanted to hear: The virus that causes COVID-19 has changed -- once again -- in ways that make it more contagious. At least one new “super strain” of the virus is already in the U.S. Another highly contagious strain from South Africa could be on its way. As bad as things are now,...
City Of United Kingdom Brown School United States New York South Africa
Source: webmd.com

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