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Chromatin-regulating enzyme found to be a key driver of common lung cancer A chromatin-regulating enzyme has been shown by in-depth interdisciplinary investigations to be a key driver of a common type of lung cancer. Drugs that target the enzyme could improve treatment and survival rates for this particular cancer. "Squamous cell carcinoma represents nearly one third of all lung cancers in humans," says KAUST structural biologist Lukasz Jaremko, who led the research along with colleagues at Sta...

An interesting new study deals with the effects of the natural mutations in the spike antigen of the SARS-CoV-2, the pathogen that is responsible for the ongoing coronavirus disease pandemic.

A team of scientists from Brazil recently explored the abilities of the UK, South African, and Brazilian variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to evade host CD8+ T cell responses induced by natural infection or vaccination. The findings reveal reduced antigenic coverage for the P.2 Brazilian lineage, indicating its ability to evade SARS-CoV-2-induced T cell responses.

The SARS-CoV-2 pathogen successfully uses multiple immune evasion mechanisms to achieve infection within its host. An intriguing new study describes one such process, which may help develop drugs to counteract the virus more effectively.

Dual-action monoclonal antibodies from an original SARS survivor show promise against COVID-19 A recent study, currently available on the bioRxiv* preprint server, indicates that a pair of dual-action monoclonal antibodies derived from an original 2003 SARS survivor could play an important role in the fight against coronavirus disease 2019 (COVID-19) due to their broadly neutralizing activity and the engagement of the immune system via effector function capabilities. Related Stories While diff...

The role of nanotechnology in the fight against COVID-19 Nanomedicine is a very powerful tool with the potential to mitigate the burden of disease by providing nanoparticle-based carriers and vaccines. A recent review by a team of interdisciplinary researchers looked at its role in the diagnostics, therapeutics, strategies and future perspectives for coronavirus disease 2019 (COVID-19). Appearing in the journal Nanomedicine, the review summarized all the exciting advances made using diverse na...

The coronavirus could still burst out of control Photo: iStockPremium Share Via Read Full Story It feels a lot longer, but it has only been a year or so since we first mixed horror with grim fascination over the likelihood of a virus having leapt upon us from a bat, and that too, with enough virulence to paralyse human life as we knew it. Scientists who placed SARS-CoV-2, the ‘zoonotic’ bug that is responsible for our misery, under examination are now largely settled on its origin. It hoppe...

For the first time, researchers have pinpointed what causes normal proteins to convert to a diseased form, causing conditions like CJD and Kuru. The...

Novel Coronavirus Jumped From Bats To Humans With Very Little Change: Scientists The new study revealed that for the first 11 months of the Covid-19 pandemic, there has been very little important genetic change observed in the coronavirus. Representational Image Outlook Web Bureau 2021-03-14T15:54:44+05:30 Novel Coronavirus Jumped From Bats To Humans With Very Little Change: Scientists outlookindia.com 2021-03-14T16:00:57+05:30 A new study suggests that the ability of ...

Last fall brought a huge surge of COVID-19 cases across the U.S. These occurred simultaneously and with similar severity almost nationwide, with little regard to the extent or enforcement of