Findings were published in Science.
The modeling technique invented by Andrey Morgun of the OSU College of Pharmacy and Natalia Shulzenko of Oregon Stateâs Carlson College of Veterinary Medicine is known as transkingdom network analysis.
The human gut microbiome is a community of more than 10 trillion microbial cells from about 1,000 different bacterial species, and transkingdom network analysis integrates multiple types of âomicsâ data â metagenomic, metabolomic, lipidomic, proteomic, etc. â in determining how interactions among specific types of gut microbes help or hinder biological functions in the host.
In this case, the microbial interactions involved how well the body responds to a type of cancer treatment known as anti-programmed cell death protein therapy, abbreviated to anti-PD-1 therapy. It allows immune cells to react more strongly to cancer.
Changes to gut microbiome helps melanoma patients respond to immunotherapy news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
OSU study: Melanoma patients respond to immunotherapy after changes to gut microbiome
CORVALLIS, Ore. (KTVZ) – Statistical modeling developed by Oregon State University researchers has confirmed that changes to melanoma patients’ gut microbiome led them to respond to a type of treatment capable of providing long-term benefit.
Findings were published in Science.
The modeling technique invented by Andrey Morgun of the OSU College of Pharmacy and Natalia Shulzenko of Oregon State’s Carlson College of Veterinary Medicine is known as transkingdom network analysis.
The human gut microbiome is a community of more than 10 trillion microbial cells from about 1,000 different bacterial species, and transkingdom network analysis integrates multiple types of “omics” data – metagenomic, metabolomic, lipidomic, proteomic, etc. – in determining how interactions among specific types of gut microbes help or hinder biological functions in the host.