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Eight of 10 hospitalized COVID-19 patients developed neurologic complications and were six times more likely than their peers to die, according to early results from a global study published yesterday in
JAMA Network Open.
Many of the conditions were mild to moderate, but half of the patients had altered brain function or structure, and almost one in five were in a coma.
Led by University of Pittsburgh researchers for the Global Consortium Study of Neurologic Dysfunction in COVID-19, the study involved 3,744 hospitalized adult COVID-19 patients at 28 centers in 13 countries from March to October 2020.
Half have acute encephalopathy
Among the patients, 82% reported neurologic symptoms, with 37% having headaches and 26% saying they lost their sense of taste or smell. Clinicians determined that 49% of the patients had acute encephalopathy (diffuse disease that alters brain function or structure), while 17% were in a coma, and 6% had strokes.
80% Hospitalised Covid-19 Patients Face Neurological Issues, Higher Mortality Risk
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The
Global Consortium Study of Neurologic Dysfunction in Covid-19 says hospital patients with clinically diagnosed neurological signs are six times more likely to die than those without.
Read More Very early on in the pandemic it became apparent that a good number of people who were sick enough to be hospitalised also developed neurological problems, said Dr Sherry Chou, lead author and associate professor of critical care medicine, neurology and neurosurgery at the University of Pittsburgh School of Medicine and the University of Pittsburgh Medical Centre (UPMC). A year later we are still fighting an unknown invisible enemy and, like in any battle, we need intel – we have to learn as much as we can about neurological impacts of Covid-19 in patients who are actively sick and in survivors.
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80% of Hospitalized COVID Patients Have Neurological Issues
Patients with clinically diagnosed neurological symptoms associated with COVID-19 are six times more likely to die in the hospital than those without the neurological complications, according to an interim analysis from the Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID).
A paper published today in JAMA Network Open presents early results of the global effort to gather information about the incidence, severity and outcomes of neurological manifestations of COVID-19 disease.
“Very early on in the pandemic, it became apparent that a good number of people who were sick enough to be hospitalized also develop neurological problems,” said lead author Sherry Chou, M.D., M.Sc., principal investigator of the consortium and associate professor of critical care medicine, neurology, and neurosurgery at the University of Pittsburgh School of Medicine and UPMC. “A year later, we are stil
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Neurological symptoms are frighteningly common among hospitalized covid-19 patients, and the symptoms are associated with a greater risk of death, a new study shows.
A paper published Tuesday in the medical journal JAMA Network Open outlines a project studying patients from around the globe. Scientists, including several at the University of Pittsburgh, analyzed data surrounding the incidence, severity and health outcomes of covid patients who experienced a litany of neurological symptoms.
“We wanted to ask this question: how many people with covid had neurological symptoms and syndromes?” said Dr. Sherry Chou, principal investigator for the study and associate professor of critical care medicine, neurology and neurosurgery at the University of Pittsburgh. “And we want to know the impact: does having neurological symptoms on top of covid impact your outcome?
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