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Keeping A Watchful Eye: Safety Reports in Geographic Atrophy Landscape

A headline year for retina disease drug development concurrently brought about research and discussion into the safety outcomes of these new agents.

United statesSan franciscoIapocec apellisDavid lallyKunzmannk apellisDilsher dhootVeeral shethIapocec charles wykoffCharles wykoffNathan steinleAvacincaptad pegolIapocec pegcetacoplanIapocec nathan steinleUniversity retinaApellis pharmaceuticalsMacula associates

David Lally, MD: Perspective on ANX007 for Geographic Atrophy

At AAO 2023, David Lally, MD describes results from the phase 2 ARCHER study and the potential benefit of intravitreal ANX007 for patients with GA.

United statesSan franciscoDavid lallyAmerican academy of ophthalmologyAnnual american academyRetina research instituteNew england retina consultants

Neuroprotective Agent Prevents Significant Vision Loss in Geographic Atrophy

Consistent vision effect with complement C1q inhibitor, despite no effect on lesion size

United statesCharles bankheadLos angelesDavid lallyMark humayunSubers huangRetina centerAmerican academy of ophthalmologyUniversity of southern californiaNew england retina consultantsAmerican academySouthern californiaMedpage todayRetinal late breaking

ANX007 is a Potential Treatment for Geographic Atrophy, According to ARCHER Study

ARCHER study demonstrated that the antibody ANX007 was time and dose dependent, robust, and not dependent on lesion growth.

United statesSan franciscoDavid lallyAmerican academy of ophthalmologyNew englandNew england retina consultantsGeographic atrophy secondaryAge related macular degenerationSelective classical complement inhibitorAnnual american academy

David Lally, MD: Efficacy of Oral APX3330 for Diabetic Retinopathy

Presented at ASRS 2023, results from the phase 2 ZETA-1 trial showed oral APX3330 missed its primary endpoint, but the consideration of a binocular treatment effect may warrant further clinical development.

United statesDavid lallyAmerican society of retina specialistsAmerican societyRetina specialistsAnnual meetingRetina research instituteNew england retina consultants

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