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Newly engineered protein could be used to develop adaptation-proof COVID vaccine

A vaccine design approach that could protect against new variants of SARS-CoV-2 the virus that causes COVID-19 but also potentially protects against other coronaviruses is one step closer to reality as a result of research at Penn State College of Medicine. The scientists used areas of the SARS-CoV-2 virus that are less susceptible to mutation to engineer proteins called immunogens, which can elicit an immune response.

Penn State scientists say they re moving closer to developing an adaptation-proof COVID-19 vaccine

Penn State scientists say they re moving closer to developing an adaptation-proof COVID-19 vaccine

Protein simulation, experiments unveil clues on origins of Parkinson s disease

 E-Mail HERSHEY, Pa. Parkinson s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins may form harmful aggregates, or groupings, that are known to contribute to the development of the disease. They said their findings could guide the development of new therapeutics to delay or even halt the progression of neurodegenerative diseases. Alpha-synuclein is a protein that helps regulate the release of neurotransmitters in the brain and is found in neurons. It exists as a single unit, but commonly joins together with other units to perform cellular functions. When too many units combine, it can lead to the formation of Lewy bodies, which are associated with neuro

Protein simulation, experiments unveil clues on origins of Parkinson s disease

Protein simulation, experiments unveil clues on origins of Parkinson s disease
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