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Genetic Treasure Trove: 451 Keys to Unlocking Prostate Cancer Mysteries

An international collaboration led by USC explored the genomes of nearly 950,000 men, finding a total of 451 variants and refining what is known about genetic risk for prostate cancer. A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with pr

187 new genetic variants linked to prostate c

<p style="text-align:start">A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk &mdash; 451 in all &mdash; through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet. The research explored the genomes of nearly 950,000 men, including major increases in representation among men from racial and ethnic groups that have often been left out of such research. The study identified 187 new genetic variants linked to prostate cancer, revising what is known about genetic risk for the disease. With these findings, the researchers improved a system they developed for measuring genetic risk so that it was more effective in predicting who would or wouldn&rsquo;t develop prostate cancer &mdash; even distinguishing between the likelihood of aggressive and less-serious cases among men of African descent.</p>

Abstract 1574238: Intratumoral INT230-6 (Cisplatin, Vinblastine, Shao) Alone or with Ipilimumab Prolonged Survival with Favorable Safety and Immune Activation in Adults with Refractory Sarcomas (NCT 03058289) -November 02, 2023 at 10:37 am EDT

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