Nuno Bas News Today

Crossing the membrane is a major challenge on the journey through the cell. Large biomolecules usually benefit from different transport strategies to overcome the lipid bilayer, so the design and synthesis of new carriers is key for the delivery of hydrophilic substances, such as pharmaceuticals, into the cell. Among these transporters, those using light as stimulus are particularly appealing due to their high precision, no chemical waste production and the possibility of remote application.

CiQUS researchers, in collaboration with Universidade Nova de Lisboa, reported new light-responsive membrane carriers for the translocation of peptide cargos inside living cells. Now published in JACS, this work paves the way for remotely controlled systems with biological and pharmaceutical applications.