Real time online nanoparticle size monitoring
Wet bead milling is used to produce nanoparticles at industrial scales. Continuous monitoring of particle size during comminution would allow real-time end-point determination and critical quality attribute monitoring, reducing operational risk and increasing insight into particle breakage kinetics.
Acta Pharm Willya Bachofen Oral Formulation Development Suspension Properties Spatially Resolved Dynamic Light Scattering Active Pharmaceutical Ingredients
Source: azonano.com