Both insulins had similar efficacy in terms of dosage and weight change but there were more episodes of hypoglycemia (blood sugar levels lower than average) with the weekly dose, say experts.
Both insulins had similar effectiveness in terms of dosage and weight change but there were more episodes of hypoglycemia (blood sugar levels lower than average) with the weekly dose. It is less likely to help people with Type 1 diabetes, those who have fluctuating levels of blood sugar, those who are ill, exercise vigorously or drink alcohol, say experts
The study, conducted by an international team of researchers, compared different doses of oral Semaglutide and found that the higher doses of 25 mg and 50 mg showed better results in reducing blood sugar levels and promoting weight loss compared to the lowest dose of 14 mg.
The superior glycemic control and weight loss compared with the current highest approved dose of 14 mg suggest that these higher doses may support individually tailored treatment goals, based not only on glucose-lowering but also body weight and cardiovascular risk reduction targets, says Dr KP Singh, Director of Endocrinology, Fortis Hospital, Mohali and the Principal Investigator of the Semaglutide trial in India