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New Drug Successfully Treats Fatty Liver Disease in Primate Model

Millions of people are affected by nonalcoholic steatohepatitis (NASH), which is a serious liver disease. A newly discovered amino acid compound has been found to successfully treat nonalcoholic fatty liver disease in non-human primates, representing a significant step towards the development of th
United States Yang Zhao Zuowen Zheng Jinpeng Zhao Eugene Chen Shuangshuang Chen

Potential drug treats fatty liver disease in

A potential drug successfully treats the severe form of nonalcoholic fatty liver disease in non-human primates — bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests. Nonalcoholic steatohepatitis (NASH) causes scarring and inflammation in the liver and is estimated to affect up to 6.5% of the global population.
United States Wayne State University Yang Zhao Zuowen Zheng Wanqing Liu Chao Xue

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Study Shows Compound Significantly Prevents Progression of Diet-Induced Non-Alcoholic Fatty Liver Disease

Dec 10 2020 Read 580 Times Rom et al report that the oral administration of the simple tri-peptide, DT-109 (Patent US8664177B2), prevents both development of non-alcoholic fatty liver disease (NAFLD) and late stage fibrosis in a murine model of diet-induced non-alcoholic steatohepatitis (NASH). The study titled, ‘Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome’ was published in Science Translational Medicine on 2 ...
United States Eugene Chen Bruce Markhan Mathew Diggle Frcpath International Working Group For Diabetic Foot Infection Diapin Therapeutics

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