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New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new "pseudo cell" formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases.
Ma Guanghui Megan Craig Institute Of Process Engineering Chinese Academy Of Sciences Process Engineering Chinese Academy

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.
United States A Hong Kong Npj Vaccines Northern Hemisphere Greenlight Biosciences Covid 19

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Study uncovers novel therapeutic target for osteoblastic lesions in prostate cancer bone metastasis

In a study published in the journal Genes & Diseases, researchers from Army Medical University and Shenzhen University investigated the pivotal role of miR-18a-5p, a microRNA, in the development and progression of osteoblastic lesions resulting from prostate cancer (PCa) bone metastasis.
Megan Craig Shenzhen University Army Medical University Prostate Cancer Ouse Model

New model paves way to understanding and preventing SUDEP in familial epilepsy

Researchers at the University of Michigan have developed a model for studying one type of familial epilepsy, opening the door to understanding—and eventually targeting—the mechanisms that lead to the disorder and its associated fatalities.
Life Sciences Institute United States Yu Wang Peng Li Danielle Ellis Michigan Medicine Comprehensive Epilepsy Center

Promising Gene-Based Approaches To Repair Lethal Lung Injury In The Elderly From COVID-19, Pneumonia, Flu, Sepsis

Discovery from the lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago offers promising treatment approaches for acute respiratory distress syndrome (ARDS) in the elderly that can be caused by severe COVID-19, pneumonia, flu or sepsis. Currently there are no pharmacological or cell-based treatments for ARDS.
Danielle Ellis Youyang Zhao Williamg Swartchild Jr Northwestern University Feinberg School Of Medicine Manne Research Institute Stanley Manne Children Research Institute

New treatment approach effectively treats the most aggressive forms of prostate cancer

Researchers at the University of Chicago Medicine Comprehensive Cancer Center established "proof-of-concept" for a new treatment approach that was able to effectively treat the most aggressive forms of prostate cancer. The treatment showed complete tumor control and long-lasting survival without side effects in a mouse model of advanced prostate cancer.
Danielle Ellis Akash Patnaik Clinical Cancer Research University Of Chicago Medicine Comprehensive Cancer Center Uchicago Medicine Comprehensive Cancer Center Prostate Cancer

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