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Bortezomib extends survival of children with newly diagnosed T-cell lymphoblastic lymphoma

The addition of bortezomib to chemotherapy significantly improved survival outcomes among children and young adults with T-cell lymphoblastic lymphoma, according to phase 3 study results published in Journal of Clinical Oncology. Additionally, radiation can be eliminated in 90% of children with T-cell acute lymphoblastic leukemia with the intensified chemotherapy regimen, researchers noted.
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Source: healio.com

Diabetes may worsen longer-term survival for adults with breast cancer

ATLANTA — Presence of diabetes and worse glycemic control were not associated with breast cancer outcomes until 8 years of follow-up, when survival rates worsened for patients with diabetes, according to study data.“In the first 5 years, glycemic control may not be a major contributor to mortality or cancer progression in most individuals with metastatic breast cancer,” Y.M.
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Source: healio.com

Greater fracture risk seen with insulin vs. metformin use for adults with type 2 diabetes

ATLANTA — Adults with type 2 diabetes who were prescribed insulin had greater risks for major osteoporotic and hip fractures than those prescribed metformin, according to study data.“Patients using insulin or sulfonylurea are at a high risk of fractures compared to metformin-only users, and the risk could be higher in nonobese and well-controlled diabetic patients,” Sung Hye
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Source: healio.com

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Monoclonal antibodies have 'good track record' in treating migraines, expert says

DENVER — Monoclonal antibodies have shown promise as an emerging treatment for migraine, Stephanie J. Nahas, MD, MSEd, FAHS, FAAN, said at the American Headache Society annual scientific meeting. “What we've learned from looking back at clinical trial data is that the monoclonal antibodies have very low numbers needed to treat, and very high numbers needed to harm —
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Source: healio.com

Chemicals found in hair products increase viability of breast cancer cells in Black women

ATLANTA — Parabens, a class of endocrine-disrupting chemicals widely found in hair and personal care products, promote viability and gene expression of a breast cancer cell line in Black women, according to data presented at ENDO 2022. Researchers evaluated the effects of three types of parabens in the HCC1500 breast cancer cell line, which is typically found in Black women of West African
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Source: healio.com

Future type 1 diabetes therapies, women's CV health among plenary sessions at ENDO 2022

Experts from across the field of endocrinology will gather in Atlanta beginning Saturday for the first in-person Endocrine Society annual meeting in 3 years. ENDO 2022 will kick off Saturday and continue through Tuesday at the Georgia World Congress Center in Atlanta. This year’s meeting will have a hybrid format, with more than 100 sessions livestreamed to a virtual platform for attendees
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Source: healio.com

The debate over ultraprocessed foods: Should they be incorporated in dietary guidelines?

Research has shown that ultraprocessed foods are associated with weight gain and an increased risk for chronic conditions. However, there is debate whether unprocessed or minimally processed foods should be recommended over ultraprocessed foods in dietary guidelines.
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Source: healio.com

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